Pharmacology data analysis for quantifying drug potency (Kd, EC50, Ki etc) was developed a century ago.

​

This analysis assumes the target density is low and the assay is at equilibrium.

​

These assumptions are often violated by new technology, e.g. in DEL and mass spec selections. We made a video and published a paper explaining the risks and how to mitigate them.

​

We also developed easy-to-use simulators to explore target density and equilibration artifacts in data analysis - see here.